For Bodybuilders

Here are some interested questions and ansvers that a lot of guys keep asking..here we gonow:

1. Testosterone: Enanthate v. Cypionate ?
Question: Can you tell me exactly what the difference is between testosterone enanthate and cypionate? If the two steroids are interchangeable, why do they make both of them?

Answer: If we’re looking at the amount of testosterone released, then the difference between the two is only two milligrams per 100 milligrams of testosterone cypionate releases 70 milligrams of free testosterone, while enanthate releases 72. That’s really not significant at all. If we look at the pharmacokinetics of the two compounds, we further see no distinction. That was made clear in a study published in 1980 in Fertility and Sterility (33[2]:201-3; 1980), which compared the effects of 200 milligrams of testosterone cypionate to 194 milligrams of testosterone enanthate. The different doses were to compensate for the differences in ester weight, so boh steroids released exactly 140 milligrams of testosterone. The study showed that cypionate and enanthate yielded identical serum concentrations of testosterone. Their patterns of release were indistinguishable, with testosterone levels peaking one to tao days after injection and slowly declining to baseline by day 10 in both cases. I know a small percentage of people are sensitive to one ester over another, but I would assume that marketing and business concerns had more to do with the appearance of both compounds in the U.S.

2. Proviron for Muscle Gain?
Question: I purchased a steroid called Proviron, but a friend said I’d never gain any muscle on it. If it is a steroid, how can that be?

Answer: Proviron is basically an oral form of dihydrotestosterone, 1-methyl DHT to be specific. DHT and Proviron are both powerful androgens, but structurally they’re also very susceptible to the enzyme 3-hydroxysteroid dehydrogenase. It’s present in high concentrations in muscle tissue and is responsible for converting DHT and Proviron in an inactive form. Ultimately, not much makes it to receptors in the muscles, which is why both steroids are poor anabolics. Proviron could provide some effect, but certainly there are better choices.

3.Difference between Boldenone and Dianabol
Question: I remember reading somewhere that boldenone and Dianabol were pretty much the same molecule; however, I know they work very differently, as I hold a lot of water on Dianabol and little when taking Equipoise. If they’re the same molecule, why is there such a difference in water retention?

Answer: Boldenone (Equipoise) and methandrostenolone (Dianabol) are indeed structurally very similar, but they also differ in important ways. I think the best way to answer your question is to take a close look at the two molecules and how they act in the body. To start with, both are derivatives of testosterone. Both were also designed to reduce the androgenic and estrogenic nature of testosterone, and to achieve that, a double-bond was added to their structures between carbons one and two. That alteration markedly slows the rate at which the steroid can aromatize and almost totally clocks its ability to reduce to a more active (dihydro) form. Essentially, boldenone is testosterone with half the estrogen and much less androgenic kick.

Methandrostenolone is boldenone with an added 7-alph methyl group to make it orally arrive, but that changes things considerably. First, it reduces the rate of estrogen conversion further by interfering with the steroid’s ability to interact with the aromatase enzyme. That’s more than compensated for by the fact that the estrogen produced is in the form of 17-alpha-methylestradiol, which has a greatly extended half-life over regular estradiol and is less bound by serum proteins. Basically, it’s superestrogen you don’t want to mess with, and it’s the reason you notice trouble when taking Dianabol and not boldenone. Although they’re structurally similar molecules, the differences in action are quite considerable.

4.Does marijuana lower testosterone levels?
Question: I’ve been a regular pot smoker for years and have been getting more serious about weight-training lately. My lifting partner keeps telling me the smoking is going to lower my testosterone level and stop me from gaining. Is that true?

Answer: No, not really. Most studies fail to find a noticeable link between testosterone levels and regular marijuana use in adults. In that respect your herb habit probably won’t interfere with your growth. On the other hand, heavy pot smoking is usually not very conducive to rigorous training for most people. It tends to make you lazy and more passive about lifting, which is a big hindrance. Provided you find the drive to go to the gym on schedule and train aggressively, though, it shouldn’t interfere with your results much.

5.Where to inject hGH somatropin ?
Question: I purchased a box of growth hormone and am about to add it to my cycle and am about to add it to my cycle. I’m just curious as to whether it’s better to inject it into my muscle or subcutaneously. I’ve heard different opinions.

Answer: It’s most recommended to inject GH subcutaneously – between the muscle and skin – as that offers a more gradual rate of release into the bloodstream. It’s also advantageous over intramuscular injections due to the fact that GH can induce lipolysis locally. That equates to noticeable loss of subcutaneous fat at the site of injections after repeated use, prompting many to use GH shots as a means of sculpting a stubborn body area such as the abdominal muscles.

6.Keeping Cholesterol in Check with Nolvadex?
Question: My training partner told me he’s taking Nolvadex, not because he’s worried about gyno but because he says it will keep his cholesterol levels in check. Does it really do that?

Answer: One of the interesting things about Nolvadex is that while it’s an anti-estrogen in many issues, it can also act as an estrogen in others. One site in particular where it acts like that is the liver, which is the same place in the body where estrogen action stimulates HDL cholesterol synthesis. As such, many find that Nolvadex can increase good cholesterol values and the HDL-to-LDL cholesterol ratio. Nolvadex is certainly not a cure-all for the cardiac health risks of steroid use, but it’s believed to at least diminish some of the negative impact those drugs can have.

7.Does Finaplix (trenbolone) Cause Gyno?
Question: Can you tell me if using Finaplix (trenbolone) can cause a person to develop gyno? I have been getting both yes and no answers to that question.

Answer: Trenbolone cannot convert to estrogen, so most think that it cannot cause gyno. And in most cases, when used alone, it doesn’t cause that side effect. There is, however, another important link to gyno, namely the progestational nature of this steroid, which should not be totally overlooked. In that regard it seems to share the same characteristics of other 19-nor (nandrolone) derived hormones, with studies showing a strong progesterone receptor. For example, one indicates trenbolone binds more avidly to the progesterone receptor that its parent nandrolone (Cancer Research, 38:4186-98; 1978), while a second surprisingly measures it to be even more active a binder in bovines than progesterone itself (Acta Pathol Microbiol Imunol Scand Suppl, 108:838-46; 2000). Receptor binding, of course, doesn’t necessarily mean it acts as a progestin in the body, but that activity does appear to be difficult to deny at this point. More and more frequently I’ve been speaking with bodybuilders who have run into gyno and have attributed it to using trenbolone. Often it occurred soon after trenbolone was added to a normally mild cycle, and on rare occasions I have heard of it happening when the steroid was used exclusively. With estrogen absent, progestational activity seems to be the only plausible explanation. We know that progesterone augments the activity of estrogens in mammary tissue and can be a trigger for gyno. Although trenbolone is itself not estrogenic, progestational activity might allow it to increase a person’s susceptibility or sensitivity to that side effect. Potentially one could notice gyno at a given level of serum estrogen that would otherwise be uneventful. I must stress that the majority of trenbolone users don’t complain about this side effect and consider it just as safe as other non-aromatizing compounds; however; the potential underlying link is still worthy of discussion.

8.My libido is gone!
Question: I recently came off a cycle of 500mg of Sustanon weekly, which lasted for about 4.5 months. It’s been six weeks since my last shot, and right now my libido is totally gone. It’s driving me crazy. How long do you think it will take for my body to recover?

Answer: It can actually be quite some time before your body rebounds naturally. A study in which participants used a weekly dose of 250 mg of testosterone enanthate illustrates that point well. When subjects stopped therapy after 21 weeks, it took as long as 18 weeks for testosterone levels to rebound to normal. That’s an extremely protracted recovery time and certainly unwelcome. To minimize the problem, athletes often work up a recovery program at the end of each cycle using HCG and anti-estrogens.

9.Anadrol and Cholesterol
Question: A guy I work with has access to Anadrol tablets. I am very anxious to try steroids to build up my physique a little, but I’ve also had borderline bad cholesterol for a number of years. Are steroids really that dangerous for me to use?

Answer: Unfavorable alterations in cholesterol values are an extremely common side effect of steroid use. Androgens in general lower the HDL-cholesterol values (the good cholesterol) and are often linked to increases in LDL (the bad cholesterol) values. Oral steroids such as Anadrol, due to the fact that they become heavily concentrated in the liver, seem to have the greatest and most rapid negative impact on lipid profiles. So that may not be an ideal choice for you. There is really no simple yes or no answer to this question. Remember that your cholesterol values are an important indicator of cardiac risk, and you’re already noticing trouble, you should at least keep your doctor apprised of what you’re doing so your risks can be monitored with the proper blood work.

10. Receding Hairline
Question: I’m a 35-year old male in good health and am interested in trying my first cycle of steroids. I have noticed a slight recession of my hairline in the past five or six years, however, and am very worried that steroid use will cause my hair to fall out. What steroid can I use that won’t convert to DHT and cause that?

Answer: Unfortunately, all anabolic/androgenic steroids can potentially aggravate the condition. The belief that only dihydrotestosterone produces the effect is erroneous. For those who have a genetic predisposition, adrogen-receptor stimulation in the scalp will gradually cause hair follicles to shrink, leading to balding. Since all anabolic/androgenic steroids mediate their effects via the androgen receptor, not even the “mildest” are immune to the possibility.

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