TESTOSTERONE ENANTHATE
Primoteston
(testosterone enanthate)
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Testosterone
Enanthate is probably the most commonly used form of testosterone by
both athletes and bodybuilders alike. Although I don´t have any hard
statistics on this, I´d be willing to bet that this form of
testosterone is the most commonly used form of testosterone on the black market today. It´s very effective for building muscle and strength, losing fat, and is cheap & readily available.
To
understand exactly how Testosterone Enanthate (a.k.a. “test enth” or
just “enth”) builds muscle and burns fat, first we´ll take a look at
androgens and what they do in the body. You see, hormones are
substances secreted by one cell, that has an effect on the functions of
another cell. Testosterone is manufactured in the Leydig´s cells of the
testes (in men). The adult male produces between 2.5 and 11mgs of Test
per day.
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Testosterone induces changes in shape,
size and also can change the appearance and the number of muscle
fibres(7). Androgens like testosterone can protect your hard earned
muscle from the catabolic (muscle wasting) glucocorticoid hormones(8),
thus inhibiting their ability to send a message to muscle cells to
release stored protein. Remember, Testosterone sends a message to
muscle cells to store more contractile protein (called actin and
myosin); glucocorticoid hormones send the opposite message. In
addition, Testosterone has the ability to increase erythropoiesis (red
blood cell production) in your kidneys(9), and a higher Red Blood Cell
(RBC) count may improve endurance via better oxygenated blood. More
RBCs can also improve recovery from strenuous physical activity.
Agression levels often rise dramatically with the use of exogenous
testosterone (15).
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All of these great benefits are
to be had with the use of test enth alone, but realistically, it will
be part of a cycle containing one or more other drugs. People who are
bulking will probably choose Deca or Eq (possibly with Dbol as well)
and those who are cutting will probably steer towards Eq and perhaps
Trenbolone. Very often users will shoot this drug once or twice a week,
but blood levels are still above baseline with this drug at around day
eight (16).Common wisdom holds that the testosterone portion of any
such cycle should be equal to or greater than any other injectable
drug(s) portion (on a mg basis)… I believe that you can get away with
less, but in general, this is a good guideline.
As
you may have suspected, Testosterones´ anabolic/androgenic effects are
dose dependant, the higher the dose the higher the muscle building
effect(10). Lets take a look at exactly what kind of results we can
expect from administration of Testosterone Enanthate:
Effects
of 20 wk of GnRH agonist plus TE administration on relative changes
(mean ± SEM) in total LBM (A), appendicular LBM (B), and trunk LBM (C)
(percent change from baseline) measured by DEXA. P values are results
for ANOVA: *, P < 0.05 vs. all other dose groups for the multiple
comparison tests using Student-Newman-Keuls; a, P < 0.05 vs. zero
change.(11)
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This chart shows that the subjects in
this test made a roughly 15% gain in Lean Body Mass from 20 weeks of
600mgs/week of testosterone Enanthate. That´s pretty impressive, but I
feel that the following set of charts is even more so:
Change
in fat-free mass (A), fat mass (B), leg press strength (C), thigh
muscle volume (D), quadriceps muscle volume (E), sexual function (F),
insulin-like growth factor I (G), and prostate-specific antigen (H).
Data are means ± SE. *Significant differences from all other groups (P
< 0.05); significant difference from 25-, 50-, and 125-mg doses (P
< 0.05); +significant difference from 25- and 50-mg doses (P <
0.05); and significant difference from 25-mg dose (P < 0.05). (14)
Now
this is very interesting. You´ll note that the most fat was lost by the
group in this study who used the highest dose (600mgs/week), and the
most Fat Free mass, Strength and Muscle Volume was gained, when
compared to any of the lower doses studied (14). Basically, the more
testosterone you use (and this holds true for almost all steroids), the
more gains you´ll get! I know that the previous statement will ruffle
some feathers in the “less is more” club, but that´s simply too bad…
more test = more muscle, more strength, more size, and less fat.
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Did the men in this study experience side effects
at the 600mg dose? Well… HDL cholesterol was lowered (but not total
cholesterol or triglyceride levels), and two guys got Acne. Not exactly
cause for a Senate Investigation, huh? (14)
Of
course, the usual nasty side effects you can get from any form of
injectable testosterone are possible with testosterone Enanthate (acne,
hairloss, prostate enlargement, and shutting down your body´s own
natural hormonal system, etc…) but they are very overstated or
controllable in many instances.
A large percentage
of those side effects occur from the body´s ability to turn
testosterone into estrogen via a metabolic pathway mediated by the
aromatase enzyme. This process, known as aromatization causes a portion
of testosterone to be converted to estrogen. Aromatase Inhibitors
(Arimidex and Letroaole, for example) can combat this very effectively,
and are usually necessary with doses over ½ a gram per week.
Now that I´ve told you all about this drug, lets talk about cost&
you
should be paying no more than $75 for a 10cc bottle of it, dosed at
200-250mgs/ml. Of course, as usual, prices fluctuate, but I´d recommend
sticking with a reputable underground lab, rather then Organon, UpJohn,
or one of the many other expensive (and often counterfeited) companies.
This drug is relatively cheap to produce, as the raw materials are very
inexpensive, and as such, should be reasonably cheap and especially
since this drug should be a consideration for inclusion in any cycle.
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17b-hydroxy-4-androsten-3-one
Testosterone base + Enanthate ester
Molecular Weight: 412.6112
Molecular Weight (base): 288.429
Molecular Weight (ester): 130.1864
Formula (base): C19 H28 O2
Formula (ester):C7 H12 O
Melting Point (base): 155
Manufacturer: Various
Effective Dose (Men): 300-2000mg+ week
Effective Dose (Women): Not recommended
Active life: 15 days
Detection Time: 3 months
Anabolic/Androgenic ratio:100/100.
References:
- Am J Physiol. 1998 Nov;275(5 Pt 1):E864-712
- J Clin Endocrinol Metab. 1997 Feb;82(2):407-13
- Am J Physiol Endocrinol Metab. 2002 Mar;282(3):E601-7.
- Curr Opin Clin Nutr Metab Care. 2004 May;7(3):271-7.
- Curr Pharm Biotechnol. 2004 Oct;5(5):459-70.
- J Clin Endocrinol Metab. 2004 Oct;89(10):5245-55.
- Anat Histol Embryol. 2003 Apr;32(2):70-9.
- J Lab Clin Med. 1995 Mar;125(3):326-33.
- Zhonghua Nan Ke Xue. 2003;9(4):248-51
- J Clin Endocrinol Metab. 2003 Apr;88(4):1478-85
- J Clin Endocrinol Metab. 2004 Feb;89(2):718-26.
- Am J Physiol. 1998 Jun;274(6 Pt 1):C1645-52.
- Biochim Biophys Acta. 1995 May 11;1244(1):117-20.
- Am J Physiol Endocrinol Metab. 2001 Dec;281(6):E1172-81.
- Health Psychol. 1990;9(6):774-91.
- Fertility and Sterility 33.
